Global market study: Diphtheria and Tetanus containing vaccines

WHO recommends that all countries: 1) follow a life course of 6 doses of Diphtheria and Tetanus (D&T)-containing vaccines and 2) replace TT with Td vaccine. As of January 2019, 108 countries have not implemented one or both of these WHO recommendations; however, two key factors, among others, are anticipated to increase country adoption of these recommendations:
• UNICEF will no longer fund or provide procurement services for supply of TT vaccine as of January 2020.
• The Gavi Board approved in principle support for DTP-containing vaccine to be used as booster doses by funding to establish platforms as catalytic support and supporting procurement beginning in 2021.
Full implementation of WHO recommendations would increase global demand for all D&T-containing vaccines by ~15% between now and 2030. The greatest change is anticipated for Td [~140M doses] and DTwP or DTwP-HepB-Hib [~50M doses]. There is sufficient supply to support country demand for all vaccine types; however, any significant shifts in the demand for aP vaccines will require strong communication and planning. Furthermore, ensuring continued availability of the current level of Td supply will be necessary to support the replacement of TT with Td and the likely increase in demand resulting from a broader booster adoption.