• SARS-CoV-2
  • Vaccine Research and Development
  • Pandemic
  • COVID-19 Vaccines
2021 — 2022

Assess the factors enabling the rapid development and approval of COVID-19 vaccines


Identify and understand the factors that accelerated COVID-19 vaccine development and authorization timelines and develop actions to replicate these factors for vaccines needed in low- and middle-income countries.

  • Focus Project
  • To identify the key factors that resulted in the high number of COVID-19 vaccines developed and approved within 12 months of detecting the first case.
  • To understand the influence of each factor on the development and approval timelines.
  • To identify the factors that could be replicated in a non-pandemic environment and key actions to be taken by Wellcome Trust to support the factors.
MMGH conducted a literature review, interviews and an online survey to identify factors that allowed for the rapid creation of the COVID-19 vaccines. From the data sources, MMGH created a framework that identified which factors significantly impacted timelines and progress of the development and approval of the vaccine. A regression model and a comparator analysis was executed to see which factors were more impactful. Two expert advisory groups were convened to review which factors could be replicated to create vaccines that have the highest impact in low- and middle-income countries.

The report identified key components and actions for the global health community to replicate to improve timelines and outcomes of vaccine development and authorization, particularly for vaccines needed in low- and middle-income countries.

Focus Area
Policy & Strategy
Project Outputs
Covid-19 vaccines: the factors that enabled unprecedented timelines for clinical development and regulatory authorisation